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PROSCI
Artikel-Nr:
(PRSI91-898)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-898
Lokale Artikelnummer::
PRSI91-898
Beschreibung:
Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI54-197)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
54-197
Lokale Artikelnummer::
PRSI54-197
Beschreibung:
Anti-ADRB3 Chicken Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(PRSI63-288)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-288
Lokale Artikelnummer::
PRSI63-288
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI2409P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2409P
Lokale Artikelnummer::
PRSI2409P
Beschreibung:
Smac peptide is used for blocking the activity of Smac/DIABLO antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3073P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3073P
Lokale Artikelnummer::
PRSI3073P
Beschreibung:
PAK6 peptide is used for blocking activity of PAK6 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-066)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-066
Lokale Artikelnummer::
PRSI42-066
Beschreibung:
Anti-SFRP4 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-246)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-246
Lokale Artikelnummer::
PRSI91-246
Beschreibung:
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-097)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-097
Lokale Artikelnummer::
PRSI42-097
Beschreibung:
Anti-TCEAL1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-576)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-576
Lokale Artikelnummer::
PRSI29-576
Beschreibung:
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6389)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6389
Lokale Artikelnummer::
PRSI6389
Beschreibung:
ATAD3B Antibody: ATAD3B is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI64-201)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
64-201
Lokale Artikelnummer::
PRSI64-201
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI22-731)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-731
Lokale Artikelnummer::
PRSI22-731
Beschreibung:
Anti-NOX5 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI96-089)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-089
Lokale Artikelnummer::
PRSI96-089
Beschreibung:
CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. The extracellular domain has the cysteinerich repeat regions, which are characteristic for many of the receptors of the TNF superfamily. Interaction of CD40 with its ligand, CD40L, leads to aggregation of CD40 molecules,which in turn interact with cytoplasmic components to initiate signaling pathways. Early studies on the CD40-CD40L system revealed its role in humoral immunity. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3), an autosomal recessive disorder characterized by an inability of B cells to undergo isotype switching, as well as an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI26-198)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-198
Lokale Artikelnummer::
PRSI26-198
Beschreibung:
Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Collagen receptor involved in collagen-induced platelet adhesion and activation. GP6 plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss. However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke (Jandrot-Perrus et al., 2000 [PubMed 10961879]).[supplied by OMIM].
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-653)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-653
Lokale Artikelnummer::
PRSI26-653
Beschreibung:
The specific function of C20orf160 is not yet known.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-920)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-920
Lokale Artikelnummer::
PRSI29-920
Beschreibung:
SLC35B1 belongs to the nucleotide-sugar transporter family and it is probable sugar transporter.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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