PROSCI
Artikel-Nr:
(PRSI18-748)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
18-748
Lokale Artikelnummer::
PRSI18-748
Beschreibung:
Anti-COX5B Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI27-270)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-270
Lokale Artikelnummer::
PRSI27-270
Beschreibung:
SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-604)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-604
Lokale Artikelnummer::
PRSI76-604
Beschreibung:
The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells. The memory CD4+ T lymphocytes express CD86 (as mRNA and protein). CD86, and the B7-1 (CD 80) molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T. B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity. The GL-1 antibody blocks the mixed lymphocyte reaction (MLR) and inhibits the T-cells stimulation by antigen-presenting cells. Mixtures of anti-B7-1 antibody and GL-1 were reported to inhibit the interaction between CD125 and its ligand with the in vivo priming of cytotoxic T lymphocytes.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI29-438)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-438
Lokale Artikelnummer::
PRSI29-438
Beschreibung:
NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI31-280)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-280
Lokale Artikelnummer::
PRSI31-280
Beschreibung:
APOBEC3F is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6231)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6231
Lokale Artikelnummer::
PRSI6231
Beschreibung:
ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI23-988)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-988
Lokale Artikelnummer::
PRSI23-988
Beschreibung:
Anti-MT-ND4 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI96-506)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-506
Lokale Artikelnummer::
PRSI96-506
Beschreibung:
Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI19-655)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-655
Lokale Artikelnummer::
PRSI19-655
Beschreibung:
Anti-ORC6 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI30-149)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-149
Lokale Artikelnummer::
PRSI30-149
Beschreibung:
The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4531)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4531
Lokale Artikelnummer::
PRSI4531
Beschreibung:
LGI1 Antibody: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, but the top band seen in the western blot is likely to be non-specific. This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI19-460)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-460
Lokale Artikelnummer::
PRSI19-460
Beschreibung:
Anti-DYNC2LI1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI62-302)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-302
Lokale Artikelnummer::
PRSI62-302
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50. For FACS starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI28-474)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-474
Lokale Artikelnummer::
PRSI28-474
Beschreibung:
ZNF605 may be involved in transcriptional regulation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4491)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4491
Lokale Artikelnummer::
PRSI4491
Beschreibung:
LGI2 Antibody: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI63-881)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-881
Lokale Artikelnummer::
PRSI63-881
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Preis auf Anfrage
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