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Boc-(S)-thiazolidine-2-carboxylic+acid
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Boc-(S)-thiazolidine-2-carboxylic+acid
Artikel-Nr:
(PRSI79-427)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-427
Lokale Artikelnummer::
PRSI79-427
Beschreibung:
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-258)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-258
Lokale Artikelnummer::
PRSI36-258
Beschreibung:
ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-686)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-686
Lokale Artikelnummer::
PRSI28-686
Beschreibung:
MKL1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-954)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-954
Lokale Artikelnummer::
PRSI28-954
Beschreibung:
PLAGL1 is a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate.This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-400)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-400
Lokale Artikelnummer::
PRSI28-400
Beschreibung:
ZBTB26 contains 4 C2H2-type zinc fingers. It may be involved in transcriptional regulation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-606)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-606
Lokale Artikelnummer::
PRSI79-606
Beschreibung:
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4843)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4843
Lokale Artikelnummer::
PRSI4843
Beschreibung:
Spred1 Antibody: The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes; it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI34-124)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-124
Lokale Artikelnummer::
PRSI34-124
Beschreibung:
In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI60-901)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-901
Lokale Artikelnummer::
PRSI60-901
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI61-724)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-724
Lokale Artikelnummer::
PRSI61-724
Beschreibung:
For WB starting dilution is: 1:1000. For IF starting dilution is: 1:25. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI33-560)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-560
Lokale Artikelnummer::
PRSI33-560
Beschreibung:
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta; the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PLGF appears to aid aldosterone mediated atherosclerosis. Serum levels of PLGF in some cases are used as a potential biomarker for disease or genetic defect. Recent research indicates that PLGF levels are lower in mothers with Down syndrome fetuses. Evidence has suggested VEGF to be an obligatory component in PLGF signaling. While VEGF homodimers and VEGF/PLGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PLGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PLGF. VEGF and PLGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI96-765)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-765
Lokale Artikelnummer::
PRSI96-765
Beschreibung:
Vasorin (VASN),a single-pass type I membrane protein, is also known as protein slit-like 2 and SLITL2, which contains one EGF-like domain, ten LRR (leucine-rich) repeats, one LRRCT domain and one LRRNT domain. VASN is expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. VASN can interact selectively and non-covalently with TGF-beta, transform growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. In general, VASN may act as an inhibitor of TGF-beta signaling.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-086)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-086
Lokale Artikelnummer::
PRSI28-086
Beschreibung:
HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. The function of this protein is not yet known.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-956)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-956
Lokale Artikelnummer::
PRSI29-956
Beschreibung:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters.Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-334)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-334
Lokale Artikelnummer::
PRSI79-334
Beschreibung:
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-064)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-064
Lokale Artikelnummer::
PRSI45-064
Beschreibung:
Anti-GIPC1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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