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BOSTER BIOLOGICAL TECHNOLOGY
Artikel-Nr:
(PRSI23-078)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-078
Lokale Artikelnummer::
PRSI23-078
Beschreibung:
Anti-BCS1L Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI27-058)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-058
Lokale Artikelnummer::
PRSI27-058
Beschreibung:
WDR51B contains 7 WD repeats. The function of the WDR51B protein remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-722)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-722
Lokale Artikelnummer::
PRSI27-722
Beschreibung:
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involves the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. ALF is a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4335P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4335P
Lokale Artikelnummer::
PRSI4335P
Beschreibung:
Strep-tag II peptide is used for blocking the activity of strep-tag II antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-793)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-793
Lokale Artikelnummer::
PRSI79-793
Beschreibung:
Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-028)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-028
Lokale Artikelnummer::
PRSI29-028
Beschreibung:
LSR has a probable role in the clearance of triglyceride-rich lipoprotein from blood. It binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-259)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-259
Lokale Artikelnummer::
PRSI63-259
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI29-594)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-594
Lokale Artikelnummer::
PRSI29-594
Beschreibung:
GPCR5A is a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. Its gene may play a role in embryonic development and epithelial cell differentiation.This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI19-903)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-903
Lokale Artikelnummer::
PRSI19-903
Beschreibung:
Anti-USP16 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI92-681)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-681
Lokale Artikelnummer::
PRSI92-681
Beschreibung:
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerises forming dimers to octamers. The degree of serum polymerisation is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-306)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-306
Lokale Artikelnummer::
PRSI63-306
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI49-403)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-403
Lokale Artikelnummer::
PRSI49-403
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 50 µl
Artikel-Nr:
(PRSI79-359)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-359
Lokale Artikelnummer::
PRSI79-359
Beschreibung:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-054)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-054
Lokale Artikelnummer::
PRSI28-054
Beschreibung:
In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPSUHL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-336)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-336
Lokale Artikelnummer::
PRSI62-336
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI25-469)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-469
Lokale Artikelnummer::
PRSI25-469
Beschreibung:
The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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