PROSCI
Artikel-Nr:
(PRSI29-028)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-028
Lokale Artikelnummer::
PRSI29-028
Beschreibung:
LSR has a probable role in the clearance of triglyceride-rich lipoprotein from blood. It binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-259)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-259
Lokale Artikelnummer::
PRSI63-259
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI29-594)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-594
Lokale Artikelnummer::
PRSI29-594
Beschreibung:
GPCR5A is a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. Its gene may play a role in embryonic development and epithelial cell differentiation.This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI19-903)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-903
Lokale Artikelnummer::
PRSI19-903
Beschreibung:
Anti-USP16 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI92-681)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-681
Lokale Artikelnummer::
PRSI92-681
Beschreibung:
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerises forming dimers to octamers. The degree of serum polymerisation is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-306)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-306
Lokale Artikelnummer::
PRSI63-306
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI49-403)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-403
Lokale Artikelnummer::
PRSI49-403
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 50 µl
Artikel-Nr:
(PRSI79-359)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-359
Lokale Artikelnummer::
PRSI79-359
Beschreibung:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-054)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-054
Lokale Artikelnummer::
PRSI28-054
Beschreibung:
In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPSUHL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-336)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-336
Lokale Artikelnummer::
PRSI62-336
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI25-469)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-469
Lokale Artikelnummer::
PRSI25-469
Beschreibung:
The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4371)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4371
Lokale Artikelnummer::
PRSI4371
Beschreibung:
TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-095)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-095
Lokale Artikelnummer::
PRSI36-095
Beschreibung:
The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI19-824)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-824
Lokale Artikelnummer::
PRSI19-824
Beschreibung:
Anti-BEST1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI79-687)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-687
Lokale Artikelnummer::
PRSI79-687
Beschreibung:
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI54-207)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
54-207
Lokale Artikelnummer::
PRSI54-207
Beschreibung:
Anti-Serine Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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