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PROSCI
Artikel-Nr:
(PRSI79-472)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-472
Lokale Artikelnummer::
PRSI79-472
Beschreibung:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI19-646)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-646
Lokale Artikelnummer::
PRSI19-646
Beschreibung:
Anti-HUS1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI96-463)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-463
Lokale Artikelnummer::
PRSI96-463
Beschreibung:
Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-611)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-611
Lokale Artikelnummer::
PRSI76-611
Beschreibung:
The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kDa type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI45-771)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-771
Lokale Artikelnummer::
PRSI45-771
Beschreibung:
Anti-Importin 8 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-959)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-959
Lokale Artikelnummer::
PRSI62-959
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI3315P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3315P
Lokale Artikelnummer::
PRSI3315P
Beschreibung:
NAIP peptide is used for blocking the activity of the NAIP antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI70-892)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
70-892
Lokale Artikelnummer::
PRSI70-892
Beschreibung:
Anti-TUBA1A Rabbit Polyclonal Antibody
VE:
1 * 250 µl
Artikel-Nr:
(PRSI46-571)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-571
Lokale Artikelnummer::
PRSI46-571
Beschreibung:
Anti-USO1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-071)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-071
Lokale Artikelnummer::
PRSI25-071
Beschreibung:
NCOA3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI32-165)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
32-165
Lokale Artikelnummer::
PRSI32-165
Beschreibung:
Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily，GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-319)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-319
Lokale Artikelnummer::
PRSI91-319
Beschreibung:
Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20% amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5487)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5487
Lokale Artikelnummer::
PRSI5487
Beschreibung:
PLEKHM3 Antibody: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-845)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-845
Lokale Artikelnummer::
PRSI25-845
Beschreibung:
HACE1 contains 6 ANK repeats and 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. HACE1 is an E3 ubiquitin-protein ligase that may function in cellular proteins degradation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-948)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-948
Lokale Artikelnummer::
PRSI63-948
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI29-005)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-005
Lokale Artikelnummer::
PRSI29-005
Beschreibung:
BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t (15;19) (q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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