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PROSCI
Artikel-Nr:
(PRSI76-514)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-514
Lokale Artikelnummer::
PRSI76-514
Beschreibung:
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gamma c, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2R alpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI76-628)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-628
Lokale Artikelnummer::
PRSI76-628
Beschreibung:
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes. CD27 is a marker of memory B cells.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI33-656)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-656
Lokale Artikelnummer::
PRSI33-656
Beschreibung:
Recognises a protein of 165 kDa, identified as Desmoglein-2 (DSG2). This monoclonal antibody Recognises the extracellular domain of human desmoglein-2. Desmoglein-2 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cytoplasmic region containing five desmoglein repeat domains which share homology with the cadherin repeats. Instead of having the HAV adhesion motif found in type I cadherins, desmogleins have R/YAL as the adhesion motif on its amino-terminal cadherin repeat. The cytoplasmic tails of desmogleins interact with desmoplakins, plakoglobin and plakophilins. In turn, these proteins link the desmogleins with the intermediate filaments. Desmoglein-2 has been shown to be important in establishing cell-cell adhesion and function in epithelial cells. Desmoglein2 was originally identified in colon carcinoma and colon, and was named HDGC (human desmoglein colon).
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI76-011)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-011
Lokale Artikelnummer::
PRSI76-011
Beschreibung:
The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32 kDa B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(PRSI24-287)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-287
Lokale Artikelnummer::
PRSI24-287
Beschreibung:
Anti-CD28 Recombinant Antibody [Clone: D665]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSIXW-7296)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-7296
Lokale Artikelnummer::
PRSIXW-7296
Beschreibung:
Interleukin-8 (IL-8). Il-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-925)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-925
Lokale Artikelnummer::
PRSI27-925
Beschreibung:
Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1; MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1; MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-594)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-594
Lokale Artikelnummer::
PRSI26-594
Beschreibung:
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF3 is required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-557)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-557
Lokale Artikelnummer::
PRSI79-557
Beschreibung:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-493)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-493
Lokale Artikelnummer::
PRSI46-493
Beschreibung:
Anti-TRIM24 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-877)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-877
Lokale Artikelnummer::
PRSI46-877
Beschreibung:
Anti-NMNAT3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-971)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-971
Lokale Artikelnummer::
PRSI27-971
Beschreibung:
2',3'-Cyclic nucleotide-3'-phosphodiesterase (CNP1 and CNP2) is the major enzyme of central nervous system myelin. It is associated with oligodendroglial plasma membrane and uncompacted myelin (myelin-like fraction), which are in contact with glial cytoplasm
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4695P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4695P
Lokale Artikelnummer::
PRSI4695P
Beschreibung:
LASS5 peptide is used for blocking the activity of LASS5 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-772)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-772
Lokale Artikelnummer::
PRSI26-772
Beschreibung:
Fatty acid amide hydrolases, such as FAAH1 and FAAH2, hydrolyze primary fatty acid amide substrates and may play a role in fatty acid catabolism.Fatty acid amide hydrolases, such as FAAH1 (FAAH; MIM 602935) and FAAH2, hydrolyze primary fatty acid amide substrates (e.g., oleamide) and may play a role in fatty acid catabolism (Wei et al., 2006 [PubMed 17015445]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI48-752)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-752
Lokale Artikelnummer::
PRSI48-752
Beschreibung:
Anti-NOS1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(PRSI4471P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4471P
Lokale Artikelnummer::
PRSI4471P
Beschreibung:
Rim3 peptide is used for blocking the activity of Slitrk6 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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