Sie suchten nach: TONBO BIOSCIENCE

Artikel-Nr: (60-4732-U100)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 60-4732-U100

Lokale Artikelnummer:: TNBO60-4732-U100

Beschreibung: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

VE: 1 * 100 µG

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Artikel-Nr: (65-4732-U100)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 65-4732-U100

Lokale Artikelnummer:: TNBO65-4732-U100

Beschreibung: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

VE: 1 * 100 µG

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Lieferant: Tonbo Biosciences

Beschreibung: The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

Artikel-Nr: (40-5874-U500)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 40-5874-U500

Lokale Artikelnummer:: TNBO40-5874-U500

Beschreibung: The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.

VE: 1 * 500 µG

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Artikel-Nr: (65-4888-U100)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 65-4888-U100

Lokale Artikelnummer:: TNBO65-4888-U100

Beschreibung: The PIP immunoglobulin is useful as an isotype-matched control. The PIP immunolglobulin is specific for Glutathione S-transferase and can be used as an isotype control for Armenian Hamster IgG antibodies.

VE: 1 * 100 µG

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Lieferant: Tonbo Biosciences

Beschreibung: The 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells. The 3.9 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on activated neutrophils, granulocytes, some types of activated T cells and intestinal intraepithelial lymphocytes (IEL). The antibody is reported to be cross-reactive with Baboon, Chimpanzee, Cynomolgus and Rhesus CD11c.

Lieferant: Tonbo Biosciences

Beschreibung: The BM8.1 antibody is specific for mouse F4/80 antigen, a 125 kDa transmembrane protein widely expressed by members of the mononuclear phagocyte system and considered to be a key marker for mature macrophage cells. F4/80 is differentially expressed during myeloid cell development, and may be regulated by certain cytokines within the tissue microenvironment. Other cell types shown to express this antigen include Langerhans cells, Kupffer cells and dendritic cell subsets. BM8.1 is widely used together with antibodies to CD115 (c-fms), CD11b and CD11c to identify myeloid / macrophage cells by flow cytometry.

Artikel-Nr: (20-4888-U100)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 20-4888-U100

Lokale Artikelnummer:: TNBO20-4888-U100

Beschreibung: The PIP immunoglobulin is useful as an isotype-matched control. The PIP immunolglobulin is specific for Glutathione S-transferase and can be used as an isotype control for Armenian Hamster IgG antibodies.

VE: 1 * 100 µG

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Lieferant: Tonbo Biosciences

Beschreibung: The M1/69 antibody reacts with mouse CD24, a cell surface molecule also known as Heat Stable Antigen (HSA). CD24 is a GPI-linked glycoprotein involved in cell adhesion and is a ligand for CD62P (P-selectin). It is expressed on erthrocytes, thymocytes, peripheral lymphocytes and myeloid lineage cells. The expression of CD24 is used to delineate stages of of lymphocyte development in the bone marrow.

Lieferant: Tonbo Biosciences

Beschreibung: The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30 - 38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).

Artikel-Nr: (50-8035-U100)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 50-8035-U100

Lokale Artikelnummer:: TNBO50-8035-U100

Beschreibung: Goat anti-Mouse IgG2b, secondary antibody, conjugated to SureLight® R-Phycoerythrin

VE: 1 * 100 µG

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Artikel-Nr: (72-8106-M001)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 72-8106-M001

Lokale Artikelnummer:: TNBO72-8106-M001

Beschreibung: Rabbit anti-Goat IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/human, mouse, or rat IgG

VE: 1 * 1 mg

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Artikel-Nr: (30-8080-M001)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 30-8080-M001

Lokale Artikelnummer:: TNBO30-8080-M001

Beschreibung: Donkey anti-Goat IgG (H&L) - Affinity Pure, Biotin Conjugate, min x w/human, mouse, rabbit or rat IgG

VE: 1 * 1 mg

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Artikel-Nr: (72-8081-M001)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 72-8081-M001

Lokale Artikelnummer:: TNBO72-8081-M001

Beschreibung: Goat anti-Chicken IgY (H&L) - Affinity Pure, HRP Conjugate

VE: 1 * 1 mg

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Artikel-Nr: (72-8105-U500)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 72-8105-U500

Lokale Artikelnummer:: TNBO72-8105-U500

Beschreibung: Goat anti-Human IgG Fc, F(ab')2 Fragment - Affinity Pure, HRP Conjugate, min x w/bovine, horse, mouse or rabbit serum proteins

VE: 1 * 0,5 mg

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Artikel-Nr: (72-8054-U500)

Lieferant: Tonbo Biosciences

Hersteller-Artikelnummer:: 72-8054-U500

Lokale Artikelnummer:: TNBO72-8054-U500

Beschreibung: Goat anti-Mouse IgG (H&L), F(ab')2 Fragment - Affinity Pure, HRP Conjugate

VE: 1 * 0,5 mg

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