3,5-Dichlorphenylboronsäurepinakolester
Lieferant:
FLUOROCHEM
Beschreibung:
2-Chlor-3,5-dinitro-α,α,α-trifluortoluol
Artikel-Nr:
(COBBPN-6145-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
PN-6145-1G
Lokale Artikelnummer::
COBBPN-6145-1G
Beschreibung:
3,5-Dichlor-4-fluorphenylboronsäurepinakolester
VE:
1 * 1 g
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Artikel-Nr:
(BOSSBS-2945R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2945R-A750
Lokale Artikelnummer::
BOSSBS-2945R-A750
Beschreibung:
Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2945R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2945R-CY7
Lokale Artikelnummer::
BOSSBS-2945R-CY7
Beschreibung:
Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).
VE:
1 * 100 µl
Lieferant:
BIONET RESEARCH
Beschreibung:
2-Chlor-N-(3,5-dimethylphenyl)acetamid
Lieferant:
COMBI-BLOCKS
Beschreibung:
3,5-Bis(trifluormethyl)phenylboronsäure
Lieferant:
Biotium
Beschreibung:
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and others. It is involved in T-cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
Lieferant:
Biotium
Beschreibung:
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and others. It is involved in T-cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
Artikel-Nr:
(J63830.MF)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J63830.MF
Lokale Artikelnummer::
ALFAJ63830.MF
Beschreibung:
3,5-Dimethyl-1-adamantanamine hydrochloride
VE:
1 * 50 mg
Artikel-Nr:
(MOLEM83808359)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M83808359
Lokale Artikelnummer::
MOLEM83808359
Beschreibung:
3,5-Dimethyl-4-isoxazolboronsäure
VE:
1 * 1 g
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Artikel-Nr:
(BOSSBS-2675R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2675R-A488
Lokale Artikelnummer::
BOSSBS-2675R-A488
Beschreibung:
a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL453137-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
453137-5G
Lokale Artikelnummer::
SIAL453137-5G
Beschreibung:
3,5-Dibrom-4-hydroxybenzaldehyd, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
FLUOROCHEM
Beschreibung:
1-Brom-3,5-difluorbenzol
Lieferant:
FLUOROCHEM
Beschreibung:
3,5-Dimethyl-4-iodisoxazol
Lieferant:
Thermo Scientific
Beschreibung:
2-Amino-3,5-dichlorpyridin
Lieferant:
Sigma-Aldrich
Beschreibung:
3,5-Dimethyl-1H-pyrazol, Sigma-Aldrich®
Preis auf Anfrage
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