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Glycols\\u00E4urenitril
Lieferant:
Spectrum Chemical
Beschreibung:
Propylene Glycol, USP is used in pharmaceutical products as an excipient solvent in oral and topical drug products. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Artikel-Nr:
(REST36231)
Lieferant:
Restek
Hersteller-Artikelnummer::
36231
Lokale Artikelnummer::
REST36231
Beschreibung:
The european pharmacopoeia/ICH Class 2 mix C consists of six components, they are 2-ethoxyethanol (160 μg/ml), ethylene glycol (620 μg/ml), formamide (220 μg/ml), 2-methoxyethanol (methyl cellosolve) (50 μg/ml), n-methylpyrrolidone (4,840 μg/m)l and sulpholane (160 μg/m)l.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-8602R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8602R
Lokale Artikelnummer::
BOSSBS-8602R
Beschreibung:
GOX is a 370 amino acid protein that is expressed in liver and pancreas. HAO1 is localized to peroxisomes and aids in organic acid metabolism via 2-hydroxyacid oxidase activity. 2-hydroxyacid oxidases, such as HAO1, are enzymes that require a flavin cofactor to oxidize 2-hydroxyacids to 2-ketoacids while reducing oxygen to hydrogen peroxide. HAO1 prefenentially oxidizes the substrate glycolate and also oxidizes other substrates, including 2-hydroxy fatty acids as well as L-?hydroxy acids of moderately short chain lengths. The oxidation of glycolate yields glyoxylate which is utilized for peroxisomal synthesis of glycine. HAO1 is also able to convert glyoxylate to oxalate. HAO1 is thought to play a role in the pathophysiology of hyperoxaluria type 1, which is caused by defects in AGXT, a peroxisomal enzyme, leading to accumulation of glyoxylate. Hyperoxaluria type 1 is characterized by an accumulation of oxalate that is thought to lead to precipitates of calcium oxalate in kidneys which can be fatal.
VE:
1 * 100 µl
Artikel-Nr:
(ICNA08642771)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
08642771
Lokale Artikelnummer::
ICNA08642771
Beschreibung:
The ImmunO™ Micro-Ouchterlony Plate is designed for specific but low affinity antisera. Such antisera require properly spaced wells and polyethylene glycol in the agarose for optimal immunoprecipitation. Each plate contains 8 ouchterlony patterns consisting of a centre well and 6 outer wells. The maximum sample volume is 10 µl in any of the wells.
VE:
1 * 5 ST
Artikel-Nr:
(997002.6002)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC997002.6002
Beschreibung:
Silicone antifoam liquid , sterilised by gamma irradiation. SAG 471 antifoam is for use in both aqueous and non-aqueous systems, imparting outstanding durability in the control of foam over time. Highly effective (even at low concentrations), it offers cost-efficient foam control for a variety of applications, including aerobic fermentation of antibiotics involving actinomycetales organisms, glycol-based coolants, heat exchange systems, adhesives, sealants, vaccines, and others. SAG 471 antifoam is self-dispersing in water.
VE:
1 * 6 L
Artikel-Nr:
(PRSI29-759)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-759
Lokale Artikelnummer::
PRSI29-759
Beschreibung:
Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
VE:
1 * 50 µG
Artikel-Nr:
(SPCMM1402-500GM)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
M1402-500GM
Lokale Artikelnummer::
SPCMM1402-500GM
Beschreibung:
Myrj(R) S100 is a polyethylene glycol ester of stearic acid. In cosmetic and personal care products it functions as a surfactant - cleansing agent in skin creams, conditioners, shampoos, body cleansers and soapless detergents. It cleans the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away. It appears as a cream-colored, waxy solid that is nearly odourless. It is easily soluble in water and acetone.
VE:
1 * 500 g
Artikel-Nr:
(PRSI91-259)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-259
Lokale Artikelnummer::
PRSI91-259
Beschreibung:
Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent alpha-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate, but it can also be active on 2-Hydroxy fatty acids, with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-570)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-570
Lokale Artikelnummer::
PRSI29-570
Beschreibung:
CYP2E1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
VE:
1 * 50 µG
Artikel-Nr:
(461-1241)
Lieferant:
LAUDA
Hersteller-Artikelnummer::
L000618
Lokale Artikelnummer::
LAUDL000618
Beschreibung:
Das Alpha Eintauchthermostat besitzt eine benutzerfreundliche Bedienkonsole mit 3 Tasten und eine große und deutliche LED-Anzeige. Dies ermöglicht eine einfache Navigation durch das Menü. Die Thermostate eigenen sich für den Einsatz bei nicht entzündlichen Flüssigkeiten (Wasser, Wasser-Glycol-Mischungen). Die Geräte ermöglichen sowohl eine interne als auch eine externe Temperaturregelung. Temperaturabweichungen von ±0,05 K gewährleisten einen präzisen Heiz- und Kühlvorgang für eine breite Palette von Anwendungen. Mit dem optionalen Pumpenumwälzset und einer Kühlschlange kann der Eintauchthermostat zu einem kompletten Temperaturregelsystem erweitert werden.
VE:
1 * 1 ST
Lieferant:
LAUDA
Beschreibung:
Die Alpha-Kältethermostate besitzen eine benutzerfreundliche Bedienkonsole mit 3 Tasten und einer großen und deutlichen LED-Anzeige. Dies ermöglicht eine einfache Navigation durch das Menü. Die Thermostate eigenen sich für den Einsatz bei nicht entzündlichen Flüssigkeiten (Wasser, Wasser-Glycol-Mischungen). Die Geräte ermöglichen sowohl eine interne als auch eine externe Temperaturregelung. Temperaturabweichungen von ±0,05 K gewährleisten einen präzisen Heiz- und Kühlvorgang für eine breite Palette von Anwendungen. Das automatische Kühlsystem ermöglicht die Kühlung über den gesamten Temperaturbereich von −25 to +100 °C. Alle Kühlthermostate besitzen ein Kompressorsystem, das nach Bedarf ein- oder ausgeschaltet werden kann. Dies spart Strom und reduziert den Verschleiß am Kompressor und führt somit zu einer längeren Lebensdauer.
Artikel-Nr:
(BOSSBS-1306R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1306R-A680
Lokale Artikelnummer::
BOSSBS-1306R-A680
Beschreibung:
Protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteines, arginines and lysines residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) (PubMed:25416785). Plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease; functions probably related to its primary function (PubMed:17015834, PubMed:20304780, PubMed:18711745, PubMed:12796482, PubMed:19229105, PubMed:25416785). It is involved in neuroprotective mechanisms like the stabilisation of NFE2L2 and PINK1 proteins, male fertility as a positive regulator of androgen signaling pathway as well as cell growth and transformation through, for instance, the modulation of NF-kappa-B signaling pathway (PubMed:12612053, PubMed:15502874, PubMed:14749723, PubMed:17015834, PubMed:21097510, PubMed:18711745). Its involvement in protein repair could also explain other unrelated functions. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death (PubMed:16390825). Required for correct mitochondrial morphology and function as well as for autophagy of dysfunctional mitochondria (PubMed:19229105, PubMed:16632486). Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking (PubMed:18711745). Regulates astrocyte inflammatory responses, may modulate lipid rafts-dependent endocytosis in astrocytes and neuronal cells (PubMed:23847046).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1306R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1306R-A750
Lokale Artikelnummer::
BOSSBS-1306R-A750
Beschreibung:
Protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteines, arginines and lysines residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) (PubMed:25416785). Plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease; functions probably related to its primary function (PubMed:17015834, PubMed:20304780, PubMed:18711745, PubMed:12796482, PubMed:19229105, PubMed:25416785). It is involved in neuroprotective mechanisms like the stabilisation of NFE2L2 and PINK1 proteins, male fertility as a positive regulator of androgen signaling pathway as well as cell growth and transformation through, for instance, the modulation of NF-kappa-B signaling pathway (PubMed:12612053, PubMed:15502874, PubMed:14749723, PubMed:17015834, PubMed:21097510, PubMed:18711745). Its involvement in protein repair could also explain other unrelated functions. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death (PubMed:16390825). Required for correct mitochondrial morphology and function as well as for autophagy of dysfunctional mitochondria (PubMed:19229105, PubMed:16632486). Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking (PubMed:18711745). Regulates astrocyte inflammatory responses, may modulate lipid rafts-dependent endocytosis in astrocytes and neuronal cells (PubMed:23847046).
VE:
1 * 100 µl
Artikel-Nr:
(8.03265.1000)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.03265.1000
Lokale Artikelnummer::
MERC8.03265.1000
Beschreibung:
Dipropylenglycol (Isomerengemisch) zur Synthese, Sigma-Aldrich®
VE:
1 * 1 L
Lieferant:
Merck
Beschreibung:
1,2-Propylenglycoldiacetat zur Synthese, Sigma-Aldrich®
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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