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3,6-Dichloropyrazine-2-carbonitrile
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3,6-Dichloropyrazine-2-carbonitrile
Lieferant:
Biotium
Beschreibung:
Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.This MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones.
Artikel-Nr:
(BOSSBS-12883R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-A750
Lokale Artikelnummer::
BOSSBS-12883R-A750
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localisation of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12883R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-CY7
Lokale Artikelnummer::
BOSSBS-12883R-CY7
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12883R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-CY3
Lokale Artikelnummer::
BOSSBS-12883R-CY3
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE73012947-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
73012947-25G
Lokale Artikelnummer::
MOLE73012947-25G
Beschreibung:
Tetrachlor-o-benzochinon
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(EHERC10660500)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10660500
Lokale Artikelnummer::
EHERC10660500
Beschreibung:
Bithionol
VE:
1 * 0,25 g
Lieferant:
MORGAN ADVANCED MATERIALS HALD
Beschreibung:
Porzellan, innen und außen glasiert Bodenfläche unglasiert.
Lieferant:
FLUOROCHEM
Beschreibung:
3',5'-Bis(trifluormethyl)propiophenon
Lieferant:
SciLabware
Beschreibung:
PYREX®, borosilicate glass, with or without spout.
Lieferant:
FLUOROCHEM
Beschreibung:
4-Fluor-3-nitrobenzonitril
Artikel-Nr:
(BOSSBS-12883R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-HRP
Lokale Artikelnummer::
BOSSBS-12883R-HRP
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12883R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-A647
Lokale Artikelnummer::
BOSSBS-12883R-A647
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
2,6-Dibrom-4-(trifluormethyl)anilin
Lieferant:
Sigma-Aldrich
Beschreibung:
Curcumin, Sigma-Aldrich®
Artikel-Nr:
(SCOT286325806)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
286325806
Lokale Artikelnummer::
SCOT286325806
Beschreibung:
DURAN®, borosilicate glass 3.3, clear.
VE:
1 * 25 ST
Artikel-Nr:
(UPOWCS00100/35)
Lieferant:
U-Power
Hersteller-Artikelnummer::
CS00100/35
Lokale Artikelnummer::
UPOWCS00100/35
Beschreibung:
Duales PE/EVA-Unterstützungssystem mit Textiloberfläche.
VE:
1 * 1 PAAR
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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