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PROSCI
Artikel-Nr:
(PRSI30-388)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-388
Lokale Artikelnummer::
PRSI30-388
Beschreibung:
ALDOC gene is a member of the class I fructose-biphosphate aldolase gene family. ALDOC is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI43-067)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
43-067
Lokale Artikelnummer::
PRSI43-067
Beschreibung:
Anti-SYT6 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-900)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-900
Lokale Artikelnummer::
PRSI28-900
Beschreibung:
ELK1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade.This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-058)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-058
Lokale Artikelnummer::
PRSI29-058
Beschreibung:
The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-369)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-369
Lokale Artikelnummer::
PRSI45-369
Beschreibung:
Anti-CBR3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI31-130)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-130
Lokale Artikelnummer::
PRSI31-130
Beschreibung:
The 5-HT1F receptor is present in both human vascular and neuronal tissue. This gene is localized at 3p12.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-039)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-039
Lokale Artikelnummer::
PRSI36-039
Beschreibung:
ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-289)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-289
Lokale Artikelnummer::
PRSI96-289
Beschreibung:
Fatty acid-binding protein 1 (FABP1) is also known as Fatty acid-binding protein, liver (FABPL), Liver-type fatty acid-binding protein (L-FABP). FABP1 / FABPL belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 / L-FABP binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. FABP-1 may be involved in intracellular lipid transport.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI6673P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6673P
Lokale Artikelnummer::
PRSI6673P
Beschreibung:
VARP peptide is used for blocking the activity of VARP antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6613)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6613
Lokale Artikelnummer::
PRSI6613
Beschreibung:
SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-215)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-215
Lokale Artikelnummer::
PRSI42-215
Beschreibung:
Anti-EML5 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-175)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-175
Lokale Artikelnummer::
PRSI92-175
Beschreibung:
Syntenin-1 is a molecule linking syndecan-mediated signalling to the cytoskeleton. Syntenin-1 is primarily localised to membrane-associated adherens junctions and focal adhesions but also found at the endoplasmic reticulum and nucleus. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. Syntenin-1 may affect cytoskeletal-membrane organisation, cell adhesion, protein trafficking, and the activation of transcription factors. It seems to function as an adapter protein, in adherens junctions may function to couple syndecans to cytoskeletal proteins or signalling components. Syntenin-1 seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) and play a role in vesicular trafficking.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-224)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-224
Lokale Artikelnummer::
PRSI90-224
Beschreibung:
LIGHT (HVEML; CD258) is a cytokine that binds to TNFRSF3/LTBR. It activates NF-kappaB, stimulates the proliferation of T cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI91-323)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-323
Lokale Artikelnummer::
PRSI91-323
Beschreibung:
alpha-Galactosidase A is a homodimeric glycoprotein that belongs to the glycosyl hydrolase 27 family. It is a lysosomal enzyme and used as a long-term enzyme replacement therapy in patients with a confirmed diagnosis of Fabry disease. alpha-Galactosidase A can hydrolyze terminal alpha-galactosyl moieties from glycolipids and glycoproteins and catalyze the hydrolysis of melibiose into galactose and glucose. Defects alpha-Galactosidase A are the cause of Fabry disease (FD) which is a rare X-linked sphingolipidosis disease with glycolipid accumulates in many tissues. The disease consists of an inborn error of glycosphingolipid catabolism. FD patients show systemic accumulation of globotriaoslyceramide (Gb3) and related glycosphingolipids in the plasma and cellular lysosomes throughout the body. Patients may show ocular deposits, febrile episodes, and burning pain in the extremities. Death results from renal failure, cardiac or cerebral complications of hypertension or other vascular disease.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-393)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-393
Lokale Artikelnummer::
PRSI29-393
Beschreibung:
SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-969)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-969
Lokale Artikelnummer::
PRSI29-969
Beschreibung:
SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in its gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.This gene, which is expressed only during embryogenesis, encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.
VE:
1 * 50 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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