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PROSCI
Artikel-Nr:
(PRSI3755P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3755P
Lokale Artikelnummer::
PRSI3755P
Beschreibung:
BMI-1 peptide is used for blocking the activity of BMI-1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-363)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-363
Lokale Artikelnummer::
PRSI42-363
Beschreibung:
Anti-SLC19A1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-505)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-505
Lokale Artikelnummer::
PRSI33-505
Beschreibung:
Recognises a protein of 33 to 55 kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI92-032)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-032
Lokale Artikelnummer::
PRSI92-032
Beschreibung:
MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It’s function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-374)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-374
Lokale Artikelnummer::
PRSI90-374
Beschreibung:
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-616)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-616
Lokale Artikelnummer::
PRSI63-616
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI62-947)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-947
Lokale Artikelnummer::
PRSI62-947
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI4461P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4461P
Lokale Artikelnummer::
PRSI4461P
Beschreibung:
Slitrk3 peptide is used for blocking the activity of Slitrk3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-450)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-450
Lokale Artikelnummer::
PRSI29-450
Beschreibung:
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-617)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-617
Lokale Artikelnummer::
PRSI46-617
Beschreibung:
Anti-RNF141 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-629)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-629
Lokale Artikelnummer::
PRSI79-629
Beschreibung:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-474)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-474
Lokale Artikelnummer::
PRSI92-474
Beschreibung:
Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-022)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-022
Lokale Artikelnummer::
PRSI31-022
Beschreibung:
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI38-141)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-141
Lokale Artikelnummer::
PRSI38-141
Beschreibung:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin 1 may act as an autocrine negative growth factor that regulates cell proliferation. It also may regulate cell apoptosis and cell differentiation. It binds beta-galactoside, CD45, CD3 and CD4. Galectin 1 inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. It is found in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney, placenta and hematopoietic cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI38-106)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-106
Lokale Artikelnummer::
PRSI38-106
Beschreibung:
RELM beta, is a secreted protein, a probable hormone, expressed only in the gastrointestinal tract, particularly the colon. The biological functions of RELM beta and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly the molecular structure of RELM beta is highly homologous to that of the adipose-derived cytokine Resistin and RELM alpha.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-947)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-947
Lokale Artikelnummer::
PRSI42-947
Beschreibung:
Anti-SLC6A8 Goat Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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