PROSCI
Artikel-Nr:
(PRSI5195)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5195
Lokale Artikelnummer::
PRSI5195
Beschreibung:
CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-814)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-814
Lokale Artikelnummer::
PRSI91-814
Beschreibung:
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5585P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5585P
Lokale Artikelnummer::
PRSI5585P
Beschreibung:
NANOG peptide is used for blocking the activity of NANOG antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-922)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-922
Lokale Artikelnummer::
PRSI91-922
Beschreibung:
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-224)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-224
Lokale Artikelnummer::
PRSI91-224
Beschreibung:
Platelet-Activating Factor Acetylhydrolase IB Subunit beta (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Cytosolic PAF-AH IB is formed of three subunits of 45 kDa (alpha), 30 kDa (beta) and 29 kDa (gamma), PAFAHB is a catalytic subunit. PAFAHB inactivates PAF by removing the acetyl group at the sn-2 position.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-116)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-116
Lokale Artikelnummer::
PRSI28-116
Beschreibung:
TBC1D10B, which belongs to the TBC1 domain family, member 10B, was experimentally validated as a Hela cell nuclei protein, currently with unknown function. TBC/rabGAP domain-containing microvillar protein binds to first PDZ domains of EBP50 and E3KARP and EBP50-PDZ and may be potentially involved in regulating membrane traffic.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI38-194)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-194
Lokale Artikelnummer::
PRSI38-194
Beschreibung:
Endostatin, a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI35-494)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-494
Lokale Artikelnummer::
PRSI35-494
Beschreibung:
Anti-AdV Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-172)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-172
Lokale Artikelnummer::
PRSI26-172
Beschreibung:
The exact function of C20orf103 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-220)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-220
Lokale Artikelnummer::
PRSI26-220
Beschreibung:
TMEM16K is a multi-pass membrane protein. It belongs to the anoctamin family. TMEM16K may act as a calcium-activated chloride channel.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4247)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4247
Lokale Artikelnummer::
PRSI4247
Beschreibung:
IEX-1 Antibody: IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-alpha. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappa B/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI1170)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1170
Lokale Artikelnummer::
PRSI1170
Beschreibung:
Bonzo Antibody: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6127)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6127
Lokale Artikelnummer::
PRSI6127
Beschreibung:
ZBTB7A Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-020)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-020
Lokale Artikelnummer::
PRSI25-020
Beschreibung:
SLC34A3 contributes to the maintenance of inorganic phosphate (Pi) concentration at the kidney.SLC34A3 contributes to the maintenance of inorganic phosphate (Pi) concentration at the kidney (Segawa et al., 2002 [PubMed 11880379]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-177)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-177
Lokale Artikelnummer::
PRSI25-177
Beschreibung:
REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. REG1B may be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-281)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-281
Lokale Artikelnummer::
PRSI25-281
Beschreibung:
FUBP1 is a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
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