Supplier >
PROSCI
Drucken
Sie suchten nach:
28 361 results were found
PROSCI
Artikel-Nr:
(PRSI33-568)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-568
Lokale Artikelnummer::
PRSI33-568
Beschreibung:
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI19-296)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-296
Lokale Artikelnummer::
PRSI19-296
Beschreibung:
Anti-TMOD1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI6223P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6223P
Lokale Artikelnummer::
PRSI6223P
Beschreibung:
MYOZAP peptide is used for blocking the activity of MYOZAP antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3605)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3605
Lokale Artikelnummer::
PRSI3605
Beschreibung:
Bit1 Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment. Bit1 (Bcl-2 inhibitor of transcription 1) was recently identified as being involved in this process. Bit1 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin-like enhancer of split (TLE) protein and induces caspase-independent apoptosis. Both AES and TLE proteins are transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. It has been suggested that Bit1-AES complexes turn off a survival-promoting gene transcription program controlled by TLE. Interestingly, apoptosis of cells transfected with Bit1 and AES could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI51-408)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
51-408
Lokale Artikelnummer::
PRSI51-408
Beschreibung:
Anti-VCAM1 Mouse Monoclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI79-840)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-840
Lokale Artikelnummer::
PRSI79-840
Beschreibung:
The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-318)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-318
Lokale Artikelnummer::
PRSI90-318
Beschreibung:
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognises beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognises alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4615)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4615
Lokale Artikelnummer::
PRSI4615
Beschreibung:
UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4265)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4265
Lokale Artikelnummer::
PRSI4265
Beschreibung:
FEZ1 Antibody: Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6407P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6407P
Lokale Artikelnummer::
PRSI6407P
Beschreibung:
SPRYD4 peptide is used for blocking the activity of SPRYD4 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-540)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-540
Lokale Artikelnummer::
PRSI79-540
Beschreibung:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI35-107)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-107
Lokale Artikelnummer::
PRSI35-107
Beschreibung:
Purified IgG fraction of antiserum covalently coupled with highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to insure adequate conjugation while preserving the maximum enzyme activity. Free enzyme is absent.
VE:
1 * 1 mL
Artikel-Nr:
(PRSI29-965)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-965
Lokale Artikelnummer::
PRSI29-965
Beschreibung:
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI70-223)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
70-223
Lokale Artikelnummer::
PRSI70-223
Beschreibung:
Anti-CCS Mouse Monoclonal Antibody
VE:
1 * 0,5 µl
Artikel-Nr:
(PRSI91-317)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-317
Lokale Artikelnummer::
PRSI91-317
Beschreibung:
FAM3C, also called interleukin-like EMT inducer, usually exist in most secretory epithelia. It belongs to the FAM3 family according to their sequence similarities. The up-regulation and/or mislocalization in breast cancer and liver carcinoma cells of FAM3C is strongly correlated with metastasis formation and survival. FAM3C can be involved in retinal laminar formation and promote epithelial to mesenchymal transition.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-068)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-068
Lokale Artikelnummer::
PRSI91-068
Beschreibung:
Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
VE:
1 * 50 µG
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
