Proteine und Peptide
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
Soy bean trypsin inhibitor
Artikel-Nr:
(PRSI91-432)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-432
Lokale Artikelnummer::
PRSI91-432
Beschreibung:
Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1 alpha, IL1 beta and IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5727P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5727P
Lokale Artikelnummer::
PRSI5727P
Beschreibung:
APC5 peptide is used for blocking the activity of APC5 antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Macrophage inflammatory protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta, and bone marrow. MIP-4 receptors include the chemokine receptor 8 (CCR8), the G protein-coupled receptor 30 (GPR30), and the phosphatidylinositol transfer protein membrane-associate 3 (PITPNM3). MIP-4 acts as a chemoattractant for naive T cells, CD4+ T cells, CD8+ T cells, and nonactivated lymphocytes. Further, MIP-4 promotes breast cancer metastasis and attenuates the activation of acute lymphocytic leukemia B cells.
Artikel-Nr:
(PRSI92-287)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-287
Lokale Artikelnummer::
PRSI92-287
Beschreibung:
Protachykinin-1(TAC1) is a secreted protein and belongs to the tachykinin family. TAC1 is encoded by the TAC1 gene. This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4951P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4951P
Lokale Artikelnummer::
PRSI4951P
Beschreibung:
ZBTB1 peptide is used for blocking the activity of ZBTB1 antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR). EGF is overexpressed in multiple tumor cell lines and promotes resistance to chemotherapy and radiation treatments.
Artikel-Nr:
(PRSI96-128)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-128
Lokale Artikelnummer::
PRSI96-128
Beschreibung:
CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins, which is also known as Activated leukocyte cell adhesion molecule (ALCAM) in human, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. CD166 is a cell adhesion molecule that binds to CD6. CD166 involved in neurite extension by neurons via heterophilic and homophilic interactions.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI91-540)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-540
Lokale Artikelnummer::
PRSI91-540
Beschreibung:
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms ( alpha, beta , gamma , and delta) with identical extracellular domains.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-412)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-412
Lokale Artikelnummer::
PRSI96-412
Beschreibung:
Insulin-like growth factor 2 (IGF-2) is also known as Somatomedin-A, IGF-II, PP9974, and is one of three protein hormones that share structural similarity to insulin. IGF-2 exerts its effects by binding to the IGF-1 receptor. IGF2 may also bind to the IGF-2 receptor (also called the cation-independent mannose 6-phosphate receptor), which acts as a signalling antagonist; that is, to prevent IGF2 responses. The major role of IGF2 is as a growth promoting hormone during gestation. In the process of Folliculogenesis, IGF2 is created by Theca cells to act in an autocrine manner on the theca cells themselves, and in a paracrine manner on Granulosa cells in the ovary. IGF2 promotes granulosa cell proliferation during the follicular phase of the menstrual cycle, acting alongside Follicle Stimulating Hormone (FSH). After ovulation has occurred, IGF-2 promotes progesterone secretion during the luteal phase of the menstrual cycle together with Luteinizing Hormone (LH). Thus, IGF2 acts as a Co-hormone together with both FSH and LH. IGF-2 may play a key role in memory and could potentially be used to treat Alzheimer's Disease. It is sometimes produced in excess in islet cell tumours, causing hypoglycemia. Doege-Potter syndrome is a paraneoplastic syndrome in which hypoglycemia is associated with the presence of one or more non-islet fibrous tumors in the pleural cavity. has been shown to interact with IGFBP3 and Transferrin.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-311)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-311
Lokale Artikelnummer::
PRSI91-311
Beschreibung:
Cystatin-S, also called Cystatin-SA-III or Salivary acidic protein, is usually expressed in submandibular and sublingual saliva but not in parotid saliva(at protein level). This protein, which is phosphorylated at both its N- and C-terminal regions, belongs to the cystatin family. Cystatin-S can function as an inhibitor to papain or ficin, it partially inhibits stem bromelain and bovine cathepsin C.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-445)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-445
Lokale Artikelnummer::
PRSI90-445
Beschreibung:
CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO + cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6707P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6707P
Lokale Artikelnummer::
PRSI6707P
Beschreibung:
GBP6 peptide is used for blocking the activity of GBP6 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4933P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4933P
Lokale Artikelnummer::
PRSI4933P
Beschreibung:
JPH4 peptide is used for blocking the activity of JPH4 antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.
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