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Proteine und Peptide
Artikel-Nr:
(PRSI92-576)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-576
Lokale Artikelnummer::
PRSI92-576
Beschreibung:
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in grey matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enablling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in Mouse melanocytes, is a reliable marker for melanoma malignancy both in biotic tissue and in serum.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-673)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-673
Lokale Artikelnummer::
PRSI96-673
Beschreibung:
Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5149P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5149P
Lokale Artikelnummer::
PRSI5149P
Beschreibung:
RUNX1 peptide is used for blocking the activity of RUNX1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5591P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5591P
Lokale Artikelnummer::
PRSI5591P
Beschreibung:
BFAR pepide is used for blocking the activity of BFAR antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4747P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4747P
Lokale Artikelnummer::
PRSI4747P
Beschreibung:
TRIM30 peptide is used for blocking the activity of TRIM30 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-300)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-300
Lokale Artikelnummer::
PRSI91-300
Beschreibung:
CD55 is a member of the RCA (regulators of complement activation) family. RCA proteins is characterized by the presence of four to 30 SCRs (short consensus repeats also called CCPs for control protein modules) in their plasmaexposed regions. CD55 containing four SCR modules is involved in the regulation of the complement cascade. CD55 is known to bind CD97 via the first SCR. It also binds physiologically generated C3 convertases with its second and third SCRs. Binding results in an accelerated “decay”, or dissociation of active C3 convertases, thus blocking the development of C’ attack complexes on nonforeign cells. It is known that viruses and bacteria also utilize multiple SCR sites for infection.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-291)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-291
Lokale Artikelnummer::
PRSI91-291
Beschreibung:
CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals following receptor-ligand contact. In T cells, CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6295P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6295P
Lokale Artikelnummer::
PRSI6295P
Beschreibung:
ROCK1 peptide is used for blocking the activity of ROCK1 antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interferon-inducible T cell alpha chemoattractant (I-TAC), or CXCL11, is expressed at high levels in leukocytes, pancreas, and liver cells. I-TAC gene expression is induced by interferons alpha (IFN-α), beta (IFN-β), and gamma (IFN-ɣ). I-TAC is the dominant ligand known to bind the chemokine receptor CXCR3, thus acting as a stronge agonist. I-TAC functions as a chemoattractant for interleukin 2 (IL-2)-activated T cells.
Artikel-Nr:
(PRSI4595P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4595P
Lokale Artikelnummer::
PRSI4595P
Beschreibung:
VPS53 peptide is used for blocking the activity of VPS53 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4621P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4621P
Lokale Artikelnummer::
PRSI4621P
Beschreibung:
LIMP2 peptide is used for blocking the activity of CSN8 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-162)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-162
Lokale Artikelnummer::
PRSI92-162
Beschreibung:
Tubulin Beta-4A Chain (TUBB4A) is a cytoplasmic peptide containing 444 amino acids. TUBB4A is a member of the Tubulin family. Tubulin is the major constituent of microtubules. Tubulin is a dimer composed of one alpha and one beta tubulin molecule; there are many forms of beta tubulins, Beta II and Beta IV Tubulin are ubiquitously expressed. Beta-III Tubulin, also known as Tubulin Beta-4, is regarded as a neuron-specific marker. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5213P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5213P
Lokale Artikelnummer::
PRSI5213P
Beschreibung:
Fibulin 3 peptide is used for blocking the activity of Fibulin 3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-170)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-170
Lokale Artikelnummer::
PRSI90-170
Beschreibung:
DLK2 regulates adipogenesis.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI7395P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7395P
Lokale Artikelnummer::
PRSI7395P
Beschreibung:
17 amino acids near the center of human NCBP1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-427)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-427
Lokale Artikelnummer::
PRSI90-427
Beschreibung:
T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumour cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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