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BIOSS INC
Artikel-Nr:
(BOSSBS-2521R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2521R-FITC
Lokale Artikelnummer::
BOSSBS-2521R-FITC
Beschreibung:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9423R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9423R
Lokale Artikelnummer::
BOSSBS-9423R
Beschreibung:
TM4-B, also known as TSPAN16 (tetraspanin-16) or TM4SF16 (transmembrane 4 superfamily member 16), is a 245 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the TM4SF family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4-B is broadly expressed in most human tissues and cell lines including neural and bone marrow derived tissues. The gene that encodes TM4-B contains nearly 31,000 bases and maps to human chromosome 19p13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0627R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0627R-A488
Lokale Artikelnummer::
BOSSBS-0627R-A488
Beschreibung:
Isoform 1: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression. Isoform 2: Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7714R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7714R-HRP
Lokale Artikelnummer::
BOSSBS-7714R-HRP
Beschreibung:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4290R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4290R-A680
Lokale Artikelnummer::
BOSSBS-4290R-A680
Beschreibung:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilisation and promotion of their activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15101R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15101R-A647
Lokale Artikelnummer::
BOSSBS-15101R-A647
Beschreibung:
Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf177 gene product has been provisionally designated C20orf177 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11637R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11637R-A488
Lokale Artikelnummer::
BOSSBS-11637R-A488
Beschreibung:
Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8726R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8726R-CY7
Lokale Artikelnummer::
BOSSBS-8726R-CY7
Beschreibung:
BZW2, also known as HSPC028 or MSTP017, is a 419 amino acid protein that contains one W2 domain and is thought to be involved in neuronal differentiation. The gene encoding BZW2 maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3302R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3302R-A647
Lokale Artikelnummer::
BOSSBS-3302R-A647
Beschreibung:
Neuronal Marker The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9172R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9172R-CY3
Lokale Artikelnummer::
BOSSBS-9172R-CY3
Beschreibung:
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11378R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11378R-HRP
Lokale Artikelnummer::
BOSSBS-11378R-HRP
Beschreibung:
Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0980R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0980R-FITC
Lokale Artikelnummer::
BOSSBS-0980R-FITC
Beschreibung:
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11991R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11991R
Lokale Artikelnummer::
BOSSBS-11991R
Beschreibung:
Anti-PPP2R5C Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9114R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9114R-A555
Lokale Artikelnummer::
BOSSBS-9114R-A555
Beschreibung:
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12532R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12532R-CY3
Lokale Artikelnummer::
BOSSBS-12532R-CY3
Beschreibung:
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4846R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4846R
Lokale Artikelnummer::
BOSSBS-4846R
Beschreibung:
Anti-F7 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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